Superoxide Dismutase (SOD) is a new enzyme preparation.It is widely distributed in the biological world, almost from animals to plants, and even from people to single-cell organisms.SOD is regarded as the most magical enzyme in life science and technology and the garbage scavenger in human body.SOD is the natural enemy of oxygen free radicals, the number one killer of oxygen free radicals in the body, and the basis of life and health.
SOD is the abbreviation of Super Oxide Dismutase, the Chinese name of superoxide dismutase, is an important antioxidant enzyme in organisms, widely distributed in various organisms, such as animals, plants, microorganisms, etc.SOD has special physiological activity and is the first substance to scavenge free radicals in organisms.The level of SOD in living organisms means an intuitive indicator of aging and death; it has been confirmed that as many as 60 diseases are caused by oxygen free radicals.It can counteract and block the damage caused by oxygen free radicals to cells, and repair damaged cells in time, and repeat the damage caused by free radicals.Due to the pressure of modern life, environmental pollution, various kinds of radiation and excessive exercise will cause the formation of oxygen free radicals in large quantities; therefore, the position of SOD in biological antioxidant mechanism is becoming more and more important!
Type of SOD: Superoxide dismutase can be divided into three types according to the different metal auxiliary groups it contains. The first is called copper (Cu) zinc (Zn) metal auxiliary group (Cu.Zn-SOD), the most common enzyme is green, mainly in the body's cytoplasm; the second is called manganese (Mn) metal auxiliary group (Mn-SOD), purple, which exists in the mitochondria and prokaryotic cells of eukaryotic cells.Intracellular; the third is called Fe-SOD, which is yellow-brown and exists in prokaryotic cells.
SOD is an active protease containing metal elements.SOD is one of the substances with drug function approved by the Ministry of Health of China, and its legal number is ECl.15.1.1; CAS [905489].
B.
赤藓糖醇生产方法
Production method of Erythritol
The production of Erythritol can be divided into two methods: chemical synthesis and biosynthesis.
Chemical Synthesis
The chemical synthesis method can react butylene glycol with hydrogen peroxide, then mix its aqueous solution with active nickel catalyst and add the inhibitor ammonia water, which will permeate hydrogen at about 0.5 MPa, and get Erythritol products after hydrogenation. However, the production efficiency of the chemical method is low, and industrial production has not yet been realized.
Microbial fermentation
The production of Erythritol by fermentation method began in the 1990s, and the production of Erythritol by microbial fermentation method has been widely used in the world.Carbon sources for Erythritol production include alkanes, monosaccharides and disaccharides. Glucose, fructose, mannose and sucrose are all good carbon sources for Erythritol production, among which D-mannose has the highest conversion rate of 31.5%.However, due to cost factors, at present, mainly starchy raw materials such as wheat or maize are degraded by enzymes to produce glucose, which is fermented and produced by high osmotic resistance yeast or other strains. Erythrosol can be produced by Candida spp., Glomus spp., Trichosporidium spp., Trigonella spp., Pichia spp.The industrial production process of Erythritol fermentation method is as follows: starch-liquefaction-saccharification-glucose production strain fermentation, filtration, monochrome separation, purification, concentration, crystallization, separation and drying, and finally Erythritol is obtained with an average yield of about 50%.The research shows that Erythritol fermentation method is affected by many factors, such as the change of osmotic pressure obviously affects the production of polyols, inorganic salts Mn2+, Cu2+ can improve the yield of Erythritol, oxygen, temperature have an impact on its yield, compared with chemical synthesis method, fermentation method has more production advantages.
C.
什么是小核菌胶
What Is Sclerotium Gum
A new kind of non-ionic salt and temperature resistant biopolysaccharide polymer, dextran, was produced by Sclerotium Gum. Scleroglucah is a kind of natural capsule polysaccharide. The solution of hard dextran has a special stability at high temperature, a good applicability in a wide range of pH value, a great tolerance for a variety of electrolytes in the presence of solution, a high degree of pseudoplasticity of the solution, and a little change in the viscosity of the solution caused by temperature rise and fall.
D.
氧化苦参碱的作用有哪些
What Are the Functions of Oxymatrine
Oxymatrine can inhibit the proliferation of endothelial cells induced by lung cancer and gastric cancer cells.
Oxymatrine has the effect of anti hepatitis B virus, can reduce the content of HBsAg and HBcAg in the liver of HBV transgenic mice, and has the same effect on both, no selective effect. Oxymatrine is a strong immunosuppressant, can inhibit the release of a variety of inflammatory factors, has a clear anti-inflammatory effect, and can induce Lak by IL-2 Therefore, it is unlikely that Oxymatrine can exert its anti HBV effect through cytokines such as IL-2.
The western use of Sophora Sophora: its original plant and hot water extract have been used for 25 years in the West. The Sophora alopecuroides alkaloid extract, which initially contains 20% Oxymatrine and matrine, was introduced into the western market by the window Research Institute in the form of tablet under the name Oxymatrine, which was listed in 1998. Its use has no side effects. In China, Sophora flavescens alkaloids are usually injected, but this method is not accepted in the west, but oral form. After oral administration, most of oxymatrine is converted into matrine; if the high blood concentration of oxymatrine is needed, injection must be relied on. However, it is not known whether the curative effect of oxymatrine is better than that of matrine in clinical trials. Chinese researchers also use matrine in tablets, which seems to work as well as injections.
There are a lot of alkaloids in Sophora flavescens, the highest of which are matrine and Oxymatrine, which account for 2% of the total dry weight of Sophora flavescens (most of them are in the form of oxymatrine), and there are other similar alkaloids: sophocarpine (c15h22n2o), sophoraol, Sophoramine, Sophoridine, isomatrine and other alkaloids. These components were first found in Sophora flavescens from 1958 to 1978.
行业新闻
A.
2017-2018美妆消费报告：抗衰用户15％是90后
2017-2018 Beauty Consumption Report:
15% of Anti-aging Users Are Post-90s
In recent years, not only more and more beautiful women around, but also delicate young people can be seen everywhere. Unconsciously, we have entered an era of "beauty value". "Beauty value" has quietly become an important indicator for people to observe all people and things.
Nandu Jingdong Consumption Research Institute released the jdnd consumption index "beauty blooming: 2017-2018 beauty consumption report" (hereinafter referred to as the "report") on the "butterfly Festival" in Jingdong. Through the detailed consumption data of 2017 skin care and beauty products, the report deeply analyzes the characteristics and latest trends of beauty consumption, and reveals the "beauty vane" of China's online market.
From the perspective of consumption performance in 2017, the meaning of beauty has changed and extended. First of all, from the beauty of the face to the beauty of image: hair care, skin care, beauty makeup, perfume, and the overall growth of face value consumption. Secondly, from the beauty of make-up to the beauty of nature: the concept of skin care is enhanced, and refined skin care has evolved into a general trend.
According to the report, the high-end skin care concept of Chinese consumers is gradually enhanced, and the skin care steps are more refined; in 2017, consumers pursue the healthy beauty of fresh naked makeup; the post-90s "middle-aged girls" have begun to focus on anti-aging; lipstick suits have been hot for two consecutive years, and people are no longer satisfied with a color of lip color.
At the same time, the report uses big data to describe the global skin care map of Chinese consumers - the most popular French brands and the fastest growing Japanese brands. From the perspective of skin care preference of all provinces, Guangxi, Hebei, Henan, Liaoning and Zhejiang attach importance to moisturizing, Hebei, Anhui, Sichuan and Chongqing attach importance to sunscreen, and Hebei, Henan, Tianjin, Shandong, Tianjin and Guangxi attach importance to aging protection.
Jingdong's big data show that in 2017, the consumption of facial skin care, perfume cosmetics, body care, perfume cosmetics and other consumer goods increased rapidly. The meaning of beauty has been broadened from "beauty of face" to "image beauty" of hair, body, skin, makeup and smell as a whole, and more fashionable contents such as temperament and taste have been added.
Among them, the obvious trend is that skin care is becoming more and more "refined".
Compared to the 2016, the consumption of eyebrow beauty was the highest year-on-year growth rate. The highest growth rate in 2017 was sunscreen, lip, essence, good skin color and good lip color, showing the healthy beauty of fresh and nude make-up in 2017.
When it comes to face, "delicate pig girl / boy" is not just a self mockery. In fact, it is also the enhancement of consumers' high-end skin care concept and the refinement of skin care steps.
On the one hand, young consumers are keen to upgrade skin care equipment. According to the data, the sales volume of beauty hardware increased with the upgrading of beauty equipment, among which the sales volume of face slimming instrument and beauty instrument increased by 69.1% year on year. The proportion of post-90s using beauty instrument is also increasing year by year. The proportion of 18-25-year-old users has gradually increased from 17.6% in 2015 to 25.9% in 2017.
On the other hand, skin care steps are becoming more and more refined. 2017 the fastest growth in sales was the eye cream, ranking first in 145.8% growth, followed by essential oils, essence and facial mask. The growth of elite products means that the growth of high-end skin care is obvious, and the essence of TOP products are high-end brands. According to the amount of consumption, SK-II fairy water, Estee Lauder small brown bottle, OLAY small white bottle, Lancome small black bottle are all the essence products that consumers are keen to buy.
Beauty makeup: nude makeup is popular
In 2016 and 2017, major fashion brands took the lead in setting off a "plain storm". The brands all have the same cold and plain look at the fashion week, and the skin of the show models is almost nude, which exudes the luster of porcelain muscle.
Consumption data shows that the categories with the highest year-on-year growth rate in 2017 are: sunscreen and lip products. Among them, the consumption of sunscreen increased by 2.1 times year-on-year, and lip products increased by 1.4 times. From the perspective of category growth, the new trend of skin care in 2017 is mainly manifested in the enhancement of awareness of skin problem prevention, focusing on building a good skin color. From the brand combination of "good skin color + good lip color", it shows the healthy beauty of consumers' pursuit of fresh nude makeup in 2017.
Young people's awareness of skin care is enhanced, and skin care is started early. In skin care consumption, anti wrinkle and moisturizing function consumption is the highest. From the 2017 average amount index, the anti wrinkle category has the highest index, ranking first, followed by the moisturizing category. In the anti-aging products, the number of users after 90 is large, accounting for nearly 15%.
From the age structure of users, high-end consumption shows a trend of youth. Among the high-end brand users, the post-90s account for 11% more than the whole station. There are also differences in the preferred high-end brands of all ages. There are also differences in the preferred high-end brands of all ages.
In 2017, the key words of beauty are eyebrows, eyes and lips. 2017 sales data shows that the sales volume of Meibi increased by 112.8% year on year, ranking first, and the sales volume of lip products increased by 80.7%, ranking second.
It's worth noting that lipstick suits have been selling well for two years in a row, becoming an essential gift for advertising - a lipstick can't represent "the new meaning of love".
According to the data, the sales volume of lipstick set in 2016 increased by three times compared with the same period last year, and increased by 1.9 times in 2017. Among them, consumer favorite star suits include: Saint Laurent square tube advertising set (3 colors), Dior lipstick lipstick, intense blue gold lipstick (Xing Xingshai), M. A C bullet head lipstick 2017 Christmas limited set mini (12 colors), Lancome new pure soft velvet lipstick suit (3 colors), Mary Dai Jia red lipstick box (6 color), Guerlain France seduction kiss lipstick suit (3 colors).
Global map: consumers love French brands and Japanese brands grow fast
In terms of average sales volume and average amount, Chinese consumers love French skin care and beauty products most. The most popular French brands among Chinese consumers include L'Oreal, Dior, Chanel, Lancome, and bio spring.
Under the "encirclement" of French products, in 2017, skin care and cosmetics products produced in Japan rose sharply, with the most significant rise. SK-II, ZA, Shiseido and other brand products are popular with Chinese consumers.
B.
赤藓糖醇有哪些优势
What are the Advantages of Erythritol
Erythritol has the following advantages over xylitol
1. Erythritol is a natural zero calorie sweetener, xylitol is caloric.
2. Erythritol is more tolerant than xylitol. All sugars and alcohols will have diarrhea when eating too much. There is a problem of tolerance, and erythritol is the most tolerated in human body.
3. The average glycemic index and insulin index of erythritol are lower than those of xylitol, so erythritol has less effect on blood glucose and has antioxidant activity.
4. A lot of sugars and alcohols will feel cool when eating. This cool feeling comes from the heat absorbed by dissolving. When dissolving, it will absorb your heat, so we feel cool. The degree of coolness of each product is expressed by the coefficient of heat of dissolution and absorption. Erythritol has the highest heat of dissolution and absorption, and its coolness is the highest.
5. In terms of production technology, erythritol is the only sugar alcohol produced by fermentation, which is closer to natural transformation and extraction. Other sugar alcohols are produced by hydrogenation, so the production process is different.
6. Erythritol is basically non hygroscopic, other sugar alcohols have different degrees of hygroscopicity, non hygroscopic will increase the application field.
7. Xylitol is mainly used in the field of candy and medicine in Europe. Although xylitol is added moderately in FDA and European regulations, the high intake of human body will cause the rise of blood sugar, diarrhea and other symptoms.